Considering B12 contributes to the production of ATP (a major process involved in energy conversion), many people with low energy levels will often be recommended to get vitamin B12 injections
This process reduces caloric intake
The researchers thus hypothesized that blocking NNMT could open a novel path to treating obesity and its metabolic complications [1, 2]
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In white adipose tissue, blocking NNMT elevated resting calorie burn, decreased adiposity, and improved insulin sensitivity in rodent models, independent of diet or activity changes (Kraus et al., Nature Medicine )
The other option would be to take a supplement, which would take many hours in the digestive process and would lose much value along the way